GHK-Cu

GHK-Cu is a naturally occurring copper-binding peptide studied for rejuvenation, tissue repair, and regenerative research. It is widely studied for its potential to support skin rejuvenation, tissue repair, wound healing, collagen production, hair follicle support, and broader regenerative research.

• Skin rejuvenation and anti-aging research
• Wound healing and scar reduction models
• Hair health and follicle research
• Collagen and elastin synthesis research
• Inflammation and oxidative stress studies
• Regenerative medicine research

• May support collagen synthesis and remodeling
• May support skin firmness and elasticity
• May promote wound healing and tissue regeneration
• May support hair follicle function
• May exhibit anti-inflammatory activity
• May provide antioxidant support
• May aid extracellular matrix repair

Reconstitution

2 mL bacteriostatic water or no-sting water

Final concentration

50 mg/mL

Starting dose

5 mg (10 units)

Syringe reference

10 units = 5 mg

Frequency

3 times per week

Research duration

4–6 weeks

Storage

Refrigerate after reconstitution

Research duration on the sheet: 4–6 weeks on the source protocol.

• 100 mg + 2 mL bacteriostatic or no-sting water = 50 mg/mL.
• 10 units = 5 mg.

• No dose-escalation schedule is specified on the source protocol.
• Source protocol uses 5 mg (10 units), three times per week.

• For educational and research purposes only.
• Limited human-research data.
• Avoid use in active or recent cancer research subjects.
• Not recommended during pregnancy or breastfeeding.
• Store appropriately after reconstitution.

Human research

Emerging

Animal research

Extensive

Mechanistic evidence

Strong

Long-term safety data

Limited

Completed published studies are listed below and labeled as in vitro, animal, or human research. Favorable and unfavorable results are both included, including cancer studies. This is not every paper on the compound, and it is not a recommendation or a dose.

The cancer-related GHK papers are a gene-expression analysis and the authors' report of a mouse sarcoma experiment. They are not human cancer trials. The fibroblast study used repair cells, including cells taken after cancer radiation.

• Topical glycyl-L-histidyl-L-lysine copper for diabetic neuropathic ulcersHuman

  People with diabetic plantar ulcers. A topical copper-peptide gel closed more of the ulcer than the gel without the peptide. This was a skin gel, not an injection.

• GHK-Cu and growth of normal and irradiated fibroblastsIn vitro

  Human skin fibroblasts, including cells taken after radiation for head and neck cancer. GHK-Cu sped doubling and raised early growth-factor output. These were repair cells, not cancer cells.

• Topical GHK-Cu on irradiated rat woundsAnimal

  Rats after radiation. A topical GHK-Cu gel did not reduce flap injury or increase blood vessels compared with ointment alone.

• GHK and cancer-related gene expressionIn vitro

  A gene-expression database ranked GHK as reversing about 70% of a 54-gene pattern tied to aggressive colon cancer. The same paper reports that GHK-copper suppressed sarcoma 180 growth in mice. This is not a human cancer trial.

• GHK-Cu and gene expression in breast and prostate cancer cellsIn vitro

  Stored profiles of MCF7 breast cancer cells and PC3 prostate cancer cells treated with GHK-Cu showed changes in cancer-related genes. The paper does not measure tumor size.

100 mg vial. Format: Lyophilized powder.