Oxytocin

Oxytocin is a naturally occurring hormone and peptide messenger made in the brain. It is often called the bonding hormone because it is associated with connection, trust, and emotional closeness. It is released during social bonding, intimacy, childbirth, and breastfeeding, and it also helps regulate contraction of smooth muscle, especially in the uterus and breast tissue. Research interest includes mood, calmness, social connection, emotional regulation, and reproductive physiology.

• Social bonding and connection support
• Trust, empathy, and emotional regulation
• Stress and calmness research
• Sexual wellness and intimacy support
• Reproductive and hormonal signaling research
• Childbirth and breastfeeding physiology

• Signals through oxytocin receptors in the brain and body
• May support feelings of trust, calmness, and bonding
• May influence calmness and stress response
• Plays a role in reproductive hormone signaling
• Supports uterine contraction and milk let-down physiology
• May affect mood and social-behavior pathways

Reconstitution

1 mL bacteriostatic water

Final concentration

10 mg/mL (10,000 mcg/mL)

Frequency

As needed

Administration

Subcutaneous injection, as noted on the sheet

Notes

Dosing is individualized to response and research goals. Read the data sheet for the syringe-unit range.

Research duration on the sheet: As needed, rather than a fixed multi-week cycle.

• 10 mg + 1 mL bacteriostatic water = 10 mg/mL.
• Unit markings and the microgram range are printed on the data sheet.

• No formal escalation schedule is included on the source protocol.
• The sheet describes use as needed, individualized to response.

• For educational and research purposes only.
• Limited human-research data.
• Avoid use in active or recent cancer research subjects.
• Use caution in pregnancy or breastfeeding contexts.
• Store appropriately after reconstitution.

Human research

Emerging

Animal research

Extensive

Mechanistic evidence

Moderate

Long-term safety data

Limited

Completed published studies are listed below and labeled as in vitro, animal, or human research. Favorable and unfavorable results are both included, including cancer studies. This is not every paper on the compound, and it is not a recommendation or a dose.

The completed cancer-cell studies linked here found more movement or invasion. Other breast-cancer cell lines in the wider literature have gone the other way.

• Oxytocin increases trust in humansHuman

  Adults. One intranasal dose increased trusting transfers in a money game, without a general increase in risk-taking.

• Oxytocin and breast-tumor endothelial cellsIn vitro

  Oxytocin increased division and movement of endothelial cells taken from human breast tumors, as well as ordinary skin endothelial cells.

• Copper-bound oxytocin and triple-negative breast cancer cellsIn vitro

  In MDA-MB-231 breast cancer cells, copper plus oxidized oxytocin increased invasion. Copper plus reduced oxytocin increased migration. The direction depended on the form of the peptide.

10 mg vial. Format: Lyophilized powder.